LC-MS Proteomics

Precision Proteomics Services


At Biogenity, we’re at the forefront of providing state-of-the-art LC-MS to empower researchers with the ability to generate proteomics-based biological insight.

LC-MS is a versatile platform that allows the discovery of biomarkers, the investigation of biological systems, and the addressing of protein concentration and post-translational modifications. LC-MS is unlike many other proteomic workflows; it is not dependent on antibodies or aptamers, which allows for the analysis of much more diverse proteins and makes experimental designs more customizable.

Biogenity provides expertise and experience, allowing you to get the right LC-MS approaches for your research aim.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your LC-MS/MS proteomics analysis.


Let’s discuss your project


+10,000 proteins
identified in deep workflows


DDA and DIA
on Orbitrap Exploris 480 and Eclipse


Relative & absolute
quantification with labeled peptides

Guiding you from sample to biology

Our team of experts is well-equipped to assist you with your discovery-based LC-MS proteomics project. We propose initiating the collaboration with an online meeting, during which we can delve into the specifics of your project. The meeting allows us to gain valuable insights into the requirements connected to the objectives. Together, we can explore various options tailored to achieving your goals.



Get a price estimate

If you need an estimate for your project, we are happy to help. We encourage you to request a free consultation to assess which discovery approach fits your proteomics research aim.


Sample preparation and sample analysis

Customized sample preparation for your proteomics

Discover how different methods allow for various proteomic approaches, whether you are looking for label-free proteomics, TMT-based proteomics, clinical proteomics, targeted proteomics, or phosphoproteomics.

At Biogenity, our dedicated team is committed to handling your samples carefully. We offer both partial and complete sample preparation workflows and are transparent. While we encourage in-house sample preparation, we highly recommend entrusting Biogenity with the sample preparation to minimize potential variance.

More than 10,000 protein identifications for discovery

At Biogenity, we offer a range of sample analysis options tailored to your needs, and our experts will assist you in selecting the most suitable approach. Our options span from budget-friendly choices to cutting-edge deep proteome coverages, with the potential for over 10,000 protein identifications based on sample types.

We conduct both data-dependent and data-independent proteomic analyses utilizing advanced mass spectrometers, including the Orbitrap Exploris 480, Orbitrap Eclipse Tribrid, and Q Exactive Classic, all sourced from Thermo Fisher Scientific.

This is what truly sets LC-MS/MS apart

Relative and absolute quantification

Absolute quantification can be achieved using isotope-labeled peptides, whereas, without these, quantification would be relative.



Highly customizable dynamic ranges

Adjusting the dynamic ranges allows you to get the depth needed for your study and adjust the price points accordingly.



Compatible with most genome-annotated species

Proteome-based discovery studies depend only on a protein sequence database to annotate analyzed protein content when proteins have been extracted LC-MS.

Adaptable to fasta files from genomics and transcriptomic experiments

Whether you are investigating cancer subgroups, species variants, or just sequenced a novel organism, your results from genomics or transcriptomics can be used to enable a tailored proteome annotation.



Identify and quantify post-translational modifications

LC-MS can identify and quantify many post-translational modifications to proteins, and some, like phosphorylation, have specialized enrichment methods allowing for improved coverages.

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Data analysis, including report, figures, and tables

From biomarker discovery to data validation

Data analysis is where you get the overview of your LC-MS-based proteome analysis. You will receive an easy-to-follow report describing the data analysis and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.



Your dedicated data scientist

Biogenity’s data analysis is much more than simply a data analysis. It offers an insight into what biology is, e.g., potentially activated or deactivated in the different conditions, without the hassle of postprocessing the data. Our team does it all: data filtration, outlier testing, variance plotting with PCA, clustering, and the statistics - and that is just with the statistical data analysis.

Delivery and discussion

Delivery, post-consultation and discussion

At the conclusion of our LC-MS/MS proteomics analysis, we ensure a seamless transition from discovery to application. We deliver detailed reports and data, followed by a post-delivery consultation to discuss your study's insights and findings.


What to expect during post-consultation:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report(s)

Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.


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