Lipid Metabolism Services

Precision Metabolomics Services


Lipids are essential to energy storage, membrane structure, and cellular signaling. Changes in lipid composition reflect shifts in metabolism, inflammation, and physiological state across tissues and systems.

At Biogenity, we quantify a wide range of lipid classes, from fatty acids to bile acids, providing detailed insight into lipid homeostasis and metabolic adaptation.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your metabolomics analysis.


Let’s discuss your project


AAAA
Text


BBBB
Text


CCCC
Text

Guiding you from sample to biology

Our metabolomics specialists collaborate with you from the start to align analytical strategy with your research goals. During a brief online consultation, we discuss your study design, sample types, and biological questions to identify the most suitable panels and combinations within the Amino Acid and Energy Metabolism platform.



Get a Project Estimate

We offer tailored cost and timeline estimates based on your project scope. Book a free consultation to discuss your analytical setup and discover how Biogenity can support your lipidomics workflow.


Sample preparation and sample analysis

Optimized workflows for diverse lipid classes

Lipid metabolites are sensitive to oxidation, temperature, and extraction conditions. We use validated Standard Operating Procedures (SOPs) to ensure stability and reproducibility across lipid subclasses.

Supported matrices include

  • Biological fluids: plasma, serum, cerebrospinal fluid, urine
  • Cells and tissues: cultured cells, tissue biopsies, microbial and plant extracts
  • Specialized matrices: feces/gut content, food and feed samples, cell media, and supernatants
  • Model systems: animal models, nutritional and clinical studies

All extraction methods are adapted to preserve lipid integrity and minimize degradation or loss of labile compounds.

Comprehensive lipid profiling by LC–MS/MS and GC–MS/MS

Our lipid metabolism workflows provide quantitative, high-resolution profiling of key lipid classes with exceptional sensitivity and reproducibility.


Our lipid metabolism panels

Fatty Acids and Derivatives

Quantifies free and esterified fatty acids, essential fatty acids, and their oxidation products. Provides insights into β-oxidation, dietary lipid metabolism, and inflammation-related lipid signaling.



Phospholipids and Sphingolipids

Targets key membrane lipids such as phosphatidylcholines, phosphatidylethanolamines, ceramides, and sphingomyelins. Reflects membrane composition, lipid remodeling, and cellular signaling pathways.



Lipid Mediators

Quantifies signaling lipids and oxidized fatty acid derivatives associated with inflammation and oxidative stress. Provides insights into how lipid composition and modification influence metabolic regulation.

Bile Acids and Sterols

Measures primary and secondary bile acids along with cholesterol and sterol intermediates. Provides information on lipid digestion, gut–liver axis function, and microbiome-related lipid metabolism.



Triglycerides

Profiles neutral lipids responsible for energy storage and mobilization. It is highly relevant for studies investigating lipid metabolism, obesity, and disorders of energy homeostasis.



PFAS (Per- and Polyfluoroalkyl Substances)

Quantifies PFAS compounds such as PFOA, PFOS, and PFNA via LC–MS/MS. These persistent contaminants are relevant for studies of exposure, endocrine disruption, and metabolic imbalance.

Lipid metabolism combo options

Core Metabolomics Combo

Combines Amino Acids and Derivatives, Energy Metabolism, and Lipid Profiling panels for a comprehensive baseline of central metabolism.



Regulatory Metabolomics Combo

Integrates Amino Acids and Derivatives, Energy Metabolism, and Lipid Mediators panels to study signaling and regulation.

Microbiome-Linked Combo

Includes Short-Chain Fatty Acids, Bile Acids, and Indoles to connect host metabolism with microbial activity.



Environmental & Impact Combo

Combines Fatty Acids, Bile Acids, and PFAS analysis to assess how environmental factors influence metabolism.

Do you want to learn more? We are happy to assist
Get in touch today

Data analysis, including report, figures, and tables

From raw data to biological interpretation

Our data analysis workflows deliver clear, publication-ready results. We handle data normalization, statistical analysis, and pathway mapping, ensuring consistent quality and reproducibility.



Visualize lipid pathways and regulation

Results include detailed quantitative tables, QC summaries, and interactive pathway visualizations highlighting enriched lipid pathways and regulatory mechanisms. These tools allow you to explore how lipid metabolism shifts between experimental conditions and connect lipidomic data with other omics layers.

Delivery and discussion

Delivery, post-consultation and discussion

At the conclusion of our metabolomics analysis, we ensure a seamless transition from discovery to application. We deliver detailed reports and data, followed by a post-delivery consultation to discuss your study's insights and findings.


What to expect during post-consultation

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report(s)

Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.


Get Started Today