Cell Lines Proteomics Analysis

Precision Proteomics Services


At Biogenity, we leverage advanced cell-line models to investigate biological mechanisms with precision and to optimize conditions for reliable experimental outcomes.

Cell lines effectively test various effects in a controlled environment, e.g., different stimuli or inhibitors. The ability to control the environment reduces variance and makes changes in the biological system of the cell line as a result of effectors more prominent. Cell lines are also used for vaccine, antibody, enzyme, and other recombinant protein production, where understanding the underline mechanism can help control and manipulate the production.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your cell line proteomics analysis.


Let’s discuss your project


+10,000 proteins
in a single study


MS3-level quantification
with isotope labeling


PTM workflows
phosphorylation, acetylation and more

Guiding you from sample to biology

At Biogenity, we understand that cell line proteomics research is a sophisticated field that demands precision, expertise, and a tailored approach. Our team of proteomics experts is dedicated to guiding you through every step of your study, ensuring your project not only succeeds but also contributes to your scientific venture.



Get a free consultation

We invite you to an online consultation, during which we can address your questions and offer an expert assessment of how our proteomics cell line strategies can be customized to meet your research goals.


Sample preparation and sample analysis

Cell line preparation for proteomics

To ensure the best proteome coverage in your samples, Biogenity has Standard Operating Procedures for cell studies. A complete proteome coverage is critical when studying cells in order to understand the biological functions hereof and changes caused by experimental design. Our workflows cover traditional proteomics and post-translational modification studies, such as phosphorylation, acetylation, etc.

Biogenity’s team works with the highest standards to ensure the best quality handling and analysis of your samples. We ensure that every aspect of the workflow is executed by specialized personnel.

More than 10,000 proteins in a study

Biogenity provides methods for deep proteome. Using the latest generation Thermo Fisher instrument, we can reach +10,000 proteins in a study. If we use isotope labeling, we can do the quantification on MS3 level, increasing accuracy. This gives you close to full cell proteome coverages.

We pride ourselves on being able to offer state-of-the-art mass spectrometry analysis, ensuring a deep coverage.

Data analysis, including report, figures, and tables

Visualisation of your cell lines

Data analysis is where you get your overview. You will receive an easy-to-follow report describing the data analysis of your cell line proteomics samples and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.



Mapping the cellular system and monitoring pathways

Biogenity's data analysis gives you an overview of biological systems, indicating enriched pathways and biological processes. This allows for mapping wherein the cellular compartments the changes are occurring, exploring the function of the individual regulated protein and looking for general enriched molecular functions. The statistical analysis gives you insight into relevant proteins. Our clustering analysis, powered by machine learning, shows the relation between the samples and if groupings within the data can be found.

Delivery and discussion

Delivery, post-consultation and discussion

At the conclusion of our cell line proteomics analysis, we ensure a seamless transition from discovery to application. We deliver detailed reports and data, followed by a post-delivery consultation to discuss your study's insights and findings.


What to expect during post-consultation:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report(s)

Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.


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