Proteome analysis

Understanding which epitopes the immune system reacts to can be helpful information when developing vaccines against pathogens and cancer. Immunopeptidomics aims to identify the peptides bound on Major Histocompatibility Complexes (MHC), which derive from the gene cluster: the human leukocyte antigen (HLA) system. This makes immunopeptidomics a powerful tool for antigen discovery.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your immunopeptides.

Let’s discuss your project

Guiding you from sample to biology

Our experts are ready to help you with your project with immunopeptidomics. Ideally, we set up an online meeting where we get to learn about your project. Here, we discuss the different options to reach your aim.

Get a price estimate within 24 hours

If you need an estimate for your project, we are happy to help. We encourage you to request an initial free consultation to assess which immunopeptidomics approach fits your research aim.

By booking a meeting, you agree to our privacy policy.

Sample preparation and Mass Spectrometry

Sample preparation for immunopeptidomics

At Biogenity, the laboratories have Standard Operating Procedures for, e.g., the elution product from immunoprecipitations. We can also handle beads immunoprecipitations. Several options are available, and we are more than happy to discuss these in a meeting, where we can find the workflow that fits you the most.

Experienced professionals

Biogenity’s team and its partners works with the highest standards to ensure the best quality handling and analysis of your samples. We collaborate with carefully selected proteomics laboratories for immunopeptidomics, ensuring that every aspect of the workflow is executed by specialized personnel.

The latest equipment from Thermo Fisher Scientific

We pride ourselves on being able to offer the latest equipment on the market. Our collaborating proteomics laboratory has the latest equipment from Thermo Fischer, ensuring a deep coverage. If you’d like to see the complete platform list, follow this link.

High sensitivity for your low abundant immune peptides

In immunopeptidomics, sensitivity is vital, as immunopeptides often are ultra-low abundant. Biogenity offers one of the most sensitive separation technologies using nano-flow liquid chromatography. The latest mass spectrometers from Thermo Fisher Scientific, the Orbitrap Exploris 480, and Orbitrap Eclipse Tribrid provide state-of-the-art sensitivity for identifying immunopeptides. All to give you the best instruments to identify the epitope of your interest.

Visualisation of your immunopeptidomics analysis

Team of experts in data analysis on immunopeptidomics

Analyzing immunopeptides can be challenging, especially the non-tryptic nature, which can raise complications. At Biogenity, we use different Machine- and Deep Learning (AI) tools designed to improve the identification of tryptic and none-tryptic immunopeptides. We provide you with the peptides, their scores, and the available information about the peptides so that you can identify novel epitopes for your research.

Including reports, tables, and figures

Data analysis is where you get the overview of your immunopeptidomics analysis. You will receive an easy-to-follow report describing the data analysis and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.

Delivery and discussion

Delivered directly to your inbox

When your immunopeptidomics analysis is ready, we deliver it directly to your inbox. Your data and reports are easy to access and secured with encryption and password protection.

You can receive your sample leftovers sent by courier, or Biogenity can safely destroy them after project completion. It is entirely up to you.

Plant a tree with Biogenity and One Tree Planted

Partnering with One Tree Planted, we want to work towards a brighter future with better treatment for diseases and a healthy planet to enjoy life. For us, our children, grandchildren, and the generations to come.

Biogenity donates a dozen trees for every project delivered to support local communities, reforestation in the Amazon rainforest, and reduce CO2 emissions. See how we are making a difference together.

Post-consultation and discussion

It is important to us that you get the most out of your experiment, which is why we always offer a post-consultation where you can ask all your questions about the results. Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.

What you can expect:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report

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