Proteomics on Tissue Samples

Precision Proteomics Services


At Biogenity, we apply advanced tissue-based analyses to capture biological complexity, enabling deeper insight into molecular changes across diverse cellular environments.

Tissue is complex and can consist of various cells and compartments. Due to the heterogeneous cellular population, it can also be an excellent method to monitor changes, e.g., inflammation. The complexity also allows for investigating distribution and interactions between cells. Working with tissue combining technics like proteomics and microscopy (e.g., immunohistochemistry) is an excellent tool for studying molecular changes, visualizing the effect on cellular space, and discovering and validating changes.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your tissue proteomics analysis.


Let’s discuss your project


Orbitrap Eclipse
high sensitivity for complex tissue


TMT at MS3 level
less variance, higher accuracy


Tissue-specific SOPs
homogenization and extraction

Guiding you from sample to biology

At Biogenity, we understand that tissue proteomics research is a sophisticated field that demands precision, expertise, and a tailored approach. Our team of proteomics experts is dedicated to guiding you through every step of your study, ensuring your project not only succeeds but also contributes to your scientific venture.



Get a free consultation

We invite you to an online consultation, during which we can address your questions and offer an expert assessment of how our proteomics tissue strategies can be customized to meet your research goals.


Sample preparation and sample analysis

Workflows for tissue samples

Tissues come in various forms, e.g., hard to soft and rich in protein or lipids. The optimal homogenizing technique and protein extraction method can change depending on tissue type. Biogenity has excellent experience with a vast amount of tissue types and Standard Operating Procedures to ensure the proteome extraction in your samples.

Biogenity’s team works with the highest standards to ensure the best quality handling and analysis of your samples. We ensure that every aspect of the workflow is executed by specialized personnel.

Proteome coverage and accuracy

Given the complex nature of tissue, coverage and accuracy becomes crucial. Mapping biological systems or identifying invading cells requires high sensitivity, which is why we offer that your samples will be analyzed on the Thermo Fisher instrument – the Orbitrap Eclipse.

The complexity of the tissue can also be a source of variance, making it essential to keep any analytical variance to the minimum. Using TMT, we can perform the quantification on MS3 level, increasing accuracy and reducing the added variance, vital for the following statistical analysis.

Data analysis, including report, figures, and tables

Visualisation of your tissue samples

Data analysis is where it all comes to shine. You will receive an easy-to-follow report describing the data analysis of you tissue samples and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have precisely the material needed, we always provide a vast number of figures and tables.



Let us be your data scientist

Biogenity’s data analysis is much more than simply a data analysis. It offers an insight into what biology is, e.g., potentially activated or deactivated in the different conditions, without the hassle of postprocessing the data. Our team does it all: data filtration, outlier testing, variance plotting with PCA, clustering, and the statistics - and that is just with the statistical data analysis.

Delivery and discussion

Delivery, post-consultation and discussion

At the conclusion of our tissue proteomics analysis, we ensure a seamless transition from discovery to application. We deliver detailed reports and data, followed by a post-delivery consultation to discuss your study's insights and findings.


What to expect during post-consultation:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report(s)

Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.


Get Started Today