At Biogenity, we're at the forefront of biomarker discovery, harnessing the capabilities of Olink-based Proteomics. This state-of-the-art platform empowers researchers to delve deep into the world of proteins, driving innovation, and broadening the horizons of scientific understanding. From seasoned proteomics researchers to those new to the field, Biogenity provides the tools, expertise, and dedication required to make every study impactful.
The Olink platform is a testament to precision and efficiency. Here's what sets it apart:
Our experts are ready to help you with your Olink-based project. You can either choose Olink Proteomics for an independent study or as a complementary part of your standard proteomic investigations. We'd love to discuss your project if you're interested in utilizing Olink proteomics to further your research. It enables us to assist you in maximizing the value of your analysis through Olink Proteomics.
We are happy to assist if you require a cost estimate for your project. We encourage you to request an initial free consultation to determine the most suitable approach for your research objectives when working with Olink.
By booking a meeting, you agree to our privacy policy.
Olink is a gateway to groundbreaking discoveries. Our panels offerings cater to various research interests, from inflammation and cytokines to oncology and neurology. With specialized panels targeting cellular processes, Olink equips you with comprehensive insights into cell regulation, development, metabolism, and organ damage.
Biogenity’s team and partners consist of a group of specialized personnel ensuring your samples get quality handling. We provide partial and complete sample preparation workflows and happily share protocols for transparency or in-house sample preparation. However, we always recommend that Biogenity does most of the sample preparation to reduce variance.
Olink's Proximity Extension Assay (PEA) technology sets a gold standard in proteomics. By integrating double recognition with DNA coupling, PEA delivers rapid, accurate, and multiplexed biomarker analyses. This robust technological powers our diverse panels, each designed meticulously for its dedicated research application.
The innovative Proximity Extension Assay (PEA) technology is the driving force behind the distinguished Olink Explore platform and the Olink Target 96 and Target 48 panels. This pioneering approach allows us to conduct extensive, multiplex protein immunoassays from small quantities of serum, plasma, or nearly any biological specimen.
Inflammation plays a crucial role in diseases, helping us understand the underlying mechanisms and features of the condition. Olink offers an extensive inflammation panel, which is currently one of the most comprehensive in the market for analyzing proteins linked to inflammatory diseases and related biological processes. It allows for efficient and resilient exploration of protein signatures, thus accelerating the discovery of human protein biomarkers associated with inflammation. The panel is designed to identify both established and pioneering biomarkers within the field of inflammation research.
Proteins are known to be linked to different types of cancer and their development. Using the Olink Oncology panels, you can gain insight into a broad range of proteins that play a critical role in various biological functions associated with cancer onset and progression. These functions include cell proliferation, differentiation, apoptosis, angiogenesis, cellular communication, and metabolic processes within cells. An extensive categorization process was undertaken to curate the proteins featured in this panel, relying on well-known bioinformatic resources such as UniProt, the Human Protein Atlas, Gene Ontology, and DisGeNET databases. If you want to target the immune system, you can also use the Olink Target 96 Immuno-Oncology. This panel allows you to investigate targets involved in promoting and inhibiting tumor immunity and chemotaxis.
Numerous proteins play a pivotal role in the cardiovascular system. Research intensively explores their connections to diseases like heart attacks, strokes, arrhythmias, and heart valve issues. Olink provides three specialized panels for proteins associated with the cardiovascular system: Olink Target 96 Cardiometabolic, Cardiovascular II, and Cardiovascular III. The proteins within these panels were categorized using well-established public bioinformatics databases such as Uniprot, Human Protein Atlas, Gene Ontology (GO), and DisGeNET.
Cytokines play a crucial role as chemical messengers in our immune system. They provide valuable insights into the modulation of cell activation, differentiation, and proliferation, and are key to understanding the immune response.
Olink's cytokine panel is an exceptional tool for studying cytokines and inflammation-related diseases, offering both absolute and relative quantification capabilities. The biomarkers have been carefully selected to provide comprehensive coverage of essential proteins associated with critical pathways in cytokine signaling and inflammatory processes, including chemokines and interleukins.
Neurological diseases such as Alzheimers, Mutiple sclerosis and Parkinson's disease, is a vast target for identifying new biomarkers for prognostic and diagnostic use. Understanding the biological processes in the nervous system is essential in mapping the diseases.
The Olink Target 96 Neuro Exploratory panel (comprising 92 proteins) is comprised of both newly explored and well-established markers, with a specific emphasis on diseases related to neurology. The panel allows analysis of critical biological processes like axon development, neurogenesis, and synapse assembly. Among the established proteins featured in this panel is Neurofilament light polypeptide, a significant marker recognized for its relevance in degenerative neurological disorders and traumatic brain injuries.
Understanding specific biological processes is crucial when analyzing disease characteristics or treatment impacts, especially concerning central biological systems. Olink presents four distinct panels focused on Cell Regulation, Development, Metabolism, and Organ Damage. Each panel encompasses 92 proteins associated with its respective process, offering a comprehensive insight into the alterations pertinent to the research study.
Let's dive into how our advanced technology maintains high throughput and multiplexing capabilities without sacrificing data integrity or assay stability.
Data analysis is where you get the overview of your Olink-based proteome analysis. You will receive an easy-to-follow report describing the data analysis and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.
Biogenity’s data analysis is much more than simply a data analysis. It offers an insight into what biology is, e.g., potentially activated or deactivated in the different conditions, without the hassle of postprocessing the data. Our team does it all: data filtration, outlier testing, variance plotting with PCA, clustering, and the statistics - and that is just with the statistical data analysis.
When your Olink-based analysis is ready, we deliver it directly to your inbox. Your data and reports are easy to access and secured with encryption and password protection.
Partnering with One Tree Planted, we want to work towards a brighter future with better treatment for diseases and a healthy planet to enjoy life. For us, our children, grandchildren, and the generations to come.
Biogenity donates a dozen trees for every project delivered to support local communities, reforestation in the Amazon rainforest, and reduce CO2 emissions. See how we are making a difference together.
It is important to us that you get the most out of your Olink-based experiment, which is why we always offer a post-consultation where you can ask all your questions about the results. Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.
What you can expect:
Proteomics
Biogenity offers global protein analysis of your samples, getting deep proteome coverages with state-of-the-art accuracy.
Discovery-based proteomicsProteomics
Are you investigating epitopes? Biogenity's immunopeptidomics workflows aim to identify the peptides bound on Major Histocompatibility Complexes (MHC).
ImmunopeptidomicsProteomics
Biogenity's degradomics workflows are ideal if you want to investigate or identify protease activity or cleavages sites.
Degradomics