The secretome is an exciting area of the proteome, which can give information about cellular communication, reaction, and state. Different classes of proteins are secreted into the extracellular space, such as cytokines and growth factors, which, e.g., can be relevant when investigating inflammation tumor development.
If you’d like to learn more, we are happy to discuss your project and help you get the most out of your secretome analysis.
Our experts are ready to help you with your secretome project. Ideally, we set up an online meeting where we get to learn about your project. Here, we discuss the different options to reach your aim.
If you need an estimate for your project, we are happy to help. We encourage you to request an initial free consultation to assess which proteomics approach fits your secretome research aim.
When working with secretome samples for proteomics, many challenges can arise. Often it is the low expressed proteins that are of interest or the media containing fetal bovine serum. At Biogenity, we can guide you through the different opportunities to overcome these challenges so that you can extract the most protein-based knowledge from your samples.
Sample preparation for proteome analysis of secretome samples sometimes begins before sampling. If you plan to do a secretome experiment, feel free to request a non-binding consultation before initiating the experiment. The Biogenity team is ready to discuss your study, so we, together, can find the solution that gives you the best proteome data to answer your research questions.
We pride ourselves on being able to offer the latest equipment on the market. Biogenity offers the latest equipment from Thermo Fisher, ensuring a deep coverage. If you’d like to see the complete platform list, follow this link.
Depending on your aim with your protein secretome study, there may be a need for global or deep proteome analysis. At Biogenity, you get access to various mass spectrometry equipment, so you only pay for the sensitivity you need.
Data analysis is where you get your overview. You will receive an easy-to-follow report describing the secretome data analysis and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.
Biogenity’s data analysis is much more than simply a data analysis. It offers an insight into what biology is, e.g., potentially activated or deactivated in the different conditions, without the hassle of postprocessing the data. Our team does it all: data filtration, outlier testing, variance plotting with PCA, clustering, and the statistics - and that is just with the statistical data analysis.
Understanding which pathways and biological processes the regulated proteins can be annotated to is helpful when investigating the secretome. At Biogenity, we will analyze your data bringing forward potentially relevant protein regulations, and annotate which pathways, biological system, molecular function, cellular components, and diseases the proteins have been associated to. Various network maps and dot-plots will give you great insight into the complexity of biology.
Bioinformatics allows for much deeper data analysis of your secretome to identify pathways, biological processes, molecular functions, cellular components, and kinases that are changing in your data. The bioinformatic data analysis includes enrichment analysis, comparative figures, and network mapping.
When your secretome analysis is ready, we deliver it directly to your inbox. Your data and reports are easy to access and secured with encryption and password protection.
You can receive your sample leftovers sent by courier, or Biogenity can safely destroy them after project completion. It is entirely up to you.
Partnering with One Tree Planted, we want to work towards a brighter future with better treatment for diseases and a healthy planet to enjoy life. For us, our children, grandchildren, and the generations to come.
Biogenity donates a dozen trees for every project delivered to support local communities, reforestation in the Amazon rainforest, and reduce CO2 emissions. See how we are making a difference together.
It is important to us that you get the most out of your experiment, which is why we always offer a post-consultation where you can ask all your questions about the results. Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.
What you can expect:
If you need help interpreting the proteomic findings, or a third-party interpretation, Biogenity's consultants are ready to assist you. Click "play" and meet one of our consultants.
Our interpretational analysis highlights strengths and limitations in the experimental design and conclusions, allowing us to recommend follow-up experiments, publication strategies, reporting, and more.