Ubiquitination Proteomics Services

Precision Proteomics Services


At Biogenity, we apply ubiquitinomics to uncover site-specific ubiquitination events, providing a comprehensive view of regulatory signaling, protein stability, and ubiquitin-chain–dependent cellular decisions.

Protein ubiquitination is involved in nearly all processes in eukaryotic cells. Proteomics using mass spectrometry enables the global unbiased identification of ubiquitinated residues on proteins. This is crucial to understanding the ubiquitination landscape of your samples. Biogenity can get you the needed overview in your experiments, from the K48-linked chains that signal protein degradation to cell fate decisions of K63-linked ubiquitin chains.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your ubiquitination proteomics analysis.


Let’s discuss your project


K48 and K63 chains
ubiquitin chain types


Site-specific mapping
via the diglycine remnant


E3 ligase enrichment
through bioinformatic analysis

Guiding you from sample to biology

At Biogenity, we understand that ubiquitination proteomics research is a sophisticated field that demands precision, expertise, and a tailored approach. Our team of proteomics experts is dedicated to guiding you through every step of your study, ensuring your project not only succeeds but also contributes to your scientific venture.



Get a free consultation

We invite you to an online consultation, during which we can address your questions and offer an expert assessment of how our Ubiquitination proteomics strategies can be customized to meet your research goals.


Sample preparation and sample analysis

Sample preparation for ubiquitination

Ubiquitinated peptides are low in abundance, so sample preparation is key. Biogenity enriches ubiquitinated peptides using the ubiquitin-specific diglycine remnant, and we always share the methods used so you know exactly how your samples have been processed.

Biogenity’s team works with the highest standards to ensure the best quality handling and analysis of your samples. We ensure that every aspect of the workflow is executed by specialized personnel.

State-of-the-art ubiquitination analysis

Working with a specialized laboratory gives you state-of-the-art results and provides you with a unique insight into the ubiquitination landscape. Contact us and learn about Biogenity's available methods and how the analysis result will fit your research aim.

The various research aims can result in various challenges. Having different instruments allows for tailoring the instrument's use to your need. Whether you are looking for high sensitivity and accuracy to detect small changes in low abundant proteins or looking for budget-friendly methods for less complex samples, we have you covered.

Data analysis, including report, figures, and tables

Identify the regulated ubiquitinated proteins

With accurate and quantitative residue mapping, Biogenity can identify the regulated ubiquitinated proteins in your samples. This enables you to increase the depth of your understanding through bioinformatic analysis, allowing you to investigate the pathways, biological processes, molecular functions, cellular components, and E3 ligases that are enriched in your data. The bioinformatics data analysis includes enrichment analysis, comparative figures, and network mapping.



Explore the ubiquitin code in your samples

The immense complexity of ubiquitin modifications is uniquely suited to large-scale proteomic analysis. When using the ubiquitin-specific diglycine remnant on ubiquitinated lysines, proteomics is able to accurately determine the specific lysine residue that is ubiquitinylated in your samples.

Delivery and discussion

Delivery, post-consultation and discussion

At the conclusion of our ubiquitination proteomics analysis, we ensure a seamless transition from discovery to application. We deliver detailed reports and data, followed by a post-delivery consultation to discuss your study's insights and findings.


What to expect during post-consultation:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report(s)

Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.


Get Started Today