Virus-based proteomics

Proteome analysis


The study of viruses and viral infections is crucial in the discovery of vaccines, treatments, and diagnostic tools. Viruses contain nucleic acids (DNA or RNA) surrounded by a protective coat of proteins, known as a capsid. As only the capsid interacts with the surroundings, analysis of the surface proteins is essential to developing vaccines, treatments, and diagnostics. Proteomics provides a vital tool for understanding virology and offers various approaches such as global proteomics, immunopeptidomics, and N-linked glycosylation.

If you’d like to learn more, we are happy to discuss your project and help you get the most out of your virus-based proteomics analysis.


Let’s discuss your project

Guiding you from sample to biology

Biogenity offers a vast number of proteomic approaches to provide insight to virology. Whether you are interested in surface proteins and properties or investigating critical drivers in the infection and immune response, Biogenity offers a free initial consultation to discuss how the different proteomic approaches provide unique information about the related biology. Ideally, we set up an online meeting where we get to learn about your project.






Get a price estimate within 24 hours

If you need an estimate for your project, we are happy to help. We encourage you to request an initial free consultation to assess which approach fits your research aim.


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Sample preparation and Mass Spectrometry

Sample preparation for virus-based proteomics

At Biogenity, your samples will be handled with care by the experienced personnel in the laboratory. They have extensive experience extracting proteins and preparing them for proteome analysis and have optimized Standard Operating Procedures for different sample types. We can handle a variety of samples; the only requirement is that the virus has been inactivated.



Experienced professionals

Biogenity’s team and its partners works with the highest standards to ensure the best quality handling and analysis of your samples. We collaborate with carefully selected laboratories for virus-based proteomics, ensuring that every aspect of the workflow is executed by specialized personnel.

High sensitivity mass spectrometry for the best coverage

Your virus-based protein samples will be analyzed on state-of-the-art mass spectrometers from Thermo Scientific. We provide the options of analyzing your virus samples on the latest generation orbitrap instruments, the Exploris 480 and the Eclipse Tribrid mass spectrometers, ensuring you deep proteome coverages.

Having different instruments allows for tailoring the instrument's use to your need. Whether you are looking for high sensitivity and accuracy to detect small changes in low abundant proteins or looking for budget-friendly methods for less complex samples, we have you covered.

Data analysis, including report, figures, and tables

Visualisation of your virus-based proteome analysis

Data analysis is where you get the overview of your virus-based proteome analysis. You will receive an easy-to-follow report describing the data analysis and results hereof, step-by-step, together with a folder containing all tables and figures. To ensure that you have the material needed, we always provide a vast number of figures and tables.



Tailored data analysis to your research question

At Biogenity, we don’t just deliver you data. We also analyze the data and put the result in the relevant context. Where you want to map regulations in biological processes and pathways or map the sequence of capsid protein or potential epitopes, we present the data in a tailored manner to quickly address your hypothesis.

Interactive plots to highlight signaling pathways

With our bioinformatic data analysis, you will also get interactive plots that allow you to explore the signaling pathways that are enriched in your data. It lets you take the regulated proteins into perspective, showing which biological pathways or biological processes are potentially up or down-regulated. This helps you get a good understanding of what is happening in the different conditions.


Download DEMO

Delivery and discussion

Delivered directly to your inbox

When your virus-based protein analysis is ready, we deliver it directly to your inbox. Your data and reports are easy to access and secured with encryption and password protection.

You can receive your sample leftovers sent by courier, or Biogenity can safely destroy them after project completion. It is entirely up to you.



Plant a tree with Biogenity and One Tree Planted

Partnering with One Tree Planted, we want to work towards a brighter future with better treatment for diseases and a healthy planet to enjoy life. For us, our children, grandchildren, and the generations to come.

Biogenity donates a dozen trees for every project delivered to support local communities, reforestation in the Amazon rainforest, and reduce CO2 emissions. See how we are making a difference together.

Post-consultation and discussion

It is important to us that you get the most out of your experiment, which is why we always offer a post-consultation where you can ask all your questions about the results. Together, we ensure that you have the best prerequisite for your further research. The consultation can also be used to explore the next step, whether you are looking to expand the project with additional omics studies or validate the results.

What you can expect:

  • Explanation of the different steps in the sample analysis
  • Discussion of the data
  • Explanation of the different steps in the data analysis
  • Q&A to the report

Other proteomics LC-MS/MS approaches

Immunopeptidomics

Proteomics

Are you investigating epitopes? Biogenity's immunopeptidomics workflows aim to identify the peptides bound on Major Histocompatibility Complexes (MHC).

Learn more
N-linked glycosylation

Proteomics

Discover the composition of N-linked glycosylations in your samples. Biogenity offers annotation and quantification of your N-Glycans.

Learn more
Discovery-based proteomics

Proteomics

Biogenity offers global protein analysis of your samples, getting deep proteome coverages with state-of-the-art accuracy.

Learn more
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